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Home > Categories > Squalane > MEG 21 Smooth Radiance ADVANCED Formula

MEG 21 Smooth Radiance ADVANCED Formula

Manufacturer discontinued. An excellent replacement is Alastin Restorative Skin Complex.

MEG 21 Smooth Radiance ADVANCED Formula

Manufacturer discontinued. An excellent replacement is Alastin Restorative Skin Complex.
Item Code:MEG-020
Packaging:1.7 oz (50 g)
Retail Price:$140.00
Out of Stock


The Next Generation Anti-Aging and Anti-Creping Treatment

MEG 21 Advanced Formula with Supplamine is a powerful and soothing anti-wrinkle/anti-creping treatment formulated specifically for hard-to-treat areas of the neck, chest, and upper arms but is gentle enough for the face. Advanced Formula has more of the active ingredients of Supplamine than our Face Treatment and is enriched with shea butter and green tea extract. It provides the most effective treatment for dry, irregular, spotted, lined, and wrinkled skin.

Skin on the neck and décolleté is tightened and smoothed with the highest concentration of Supplamine available in the MEG 21 product line. The ingredients in Supplamine have been tested in laboratory In Vitro cell and tissue culture experiments. The ingredients in these laboratory studies have been demonstrated to intercept and reverse glycation, inflammation and metabolic oxidation caused by the same toxic sugars formed in skin, which in turn cause skin aging. MEG 21 with Supplamine is fully validated through rigorous scientific research and clinical trials that provide proof of efficacy for Supplamine, MEG 21’s proprietary patented ingredient. Also contains Jojoba Oil, Shea Butter and Squalene, all designed to increase natural moisture within the skin. With the power of Vitamin E and Green Tea, this potent formula is packed with antioxidants and anti-inflammatories. Ideal for dry skin.

Key Ingredients:
  • Supplamine - Patented ingredient to intercept and reverse glycation, inflammation and metabolic oxidation caused by 3DG sugars in the skin
  • Jojoba Oil - Emolliency similar to natural oil structure produced by the skin
  • Evening Primrose - Clears pathway to allow barrier penetration
  • Squalene - Hydrates by increasing natural moisture within the skin
  • Vitamin E - Healing antioxidant
  • Aloe - Natural anti-irritant to reduce inflammation
  • Shea Butter - Natural antioxidant rich emollient
  • Green Tea - Potent antioxidant and anti-inflammatory


  • Visible, measurable results in mature skin in 30 days or less.
  • Diminishes the visible signs of aging skin for all ages. Just one pump from dosed, airless jar twice a day does it!
  • Repairs, firms, lifts and tones crepey, sagging, wrinkled mature skin. Ideal for use on face, neck, throat, jowls and crinkly lips. Evens skin tone and gently lightens freckles and age spots over time.
  • Exclusively contains patented Supplamine, a unique, powerful skin anti-aging ingredient, proven highly effective in 9 independent, dermatologist-conducted clinical trials with over 125 subjects, 40 to 60 years of age. Also contains natural amino acids to positively effect collagen and elastin in skin.
  • Especially effective on "loose neck skin", tightens and smooths problem skin on upper arms, chest and neck but gentle enough for the face
  • Clinically proven to reverse the appearance of fine lines and wrinkles in 28 days
  • Maximum strength formula to promote natural collagen production and improve overall skin appearance on neck, chest, and upper arms
  • Improved skin texture
  • Gently massage into areas where skin is droopy, crepy, or lined and wrinkled
  • Recommended for all skin types, just "twist and pump"
  • Allergy tested, scientifically formulated, non-irritating anti-aging treatment
  • Contains Supplamine, a unique patented anti-glycation formulation that counteracts the effects of glycation and oxidative stress on skin
  • Great under make-up, sunscreen, or moisturizer
  • Product is packaged in an airless pop-up jar. The pump's unique dispenser protects product from air exposure and contamination. The pump can also be opened for good-to-the-last-drop usage.


Apply 2 pumps of MEG 21 Advanced Formula twice daily to freshly cleansed and toned throat, neck and chest. Apply with gentle upward strokes, beginning with the area just below the ear lobes, then to the chin, throat and chest. Gentle enough for the face. When going outside use over MEG 21 Anti-Oxidant Boost. Follow with a sunscreen in the morning.

To dispense, lift off, without twisting cap; gently press down on white disc using two thumbs to pump. When using the airless jar for the first time, you might need to “prime” by slowly pressing down on the white disc several times. This process of “priming” will activate the vacuum pump system.


Water (Aqua), Lecithin, Propylene Glycol, Cyclopentasiloxane, Theobroma Cacao Seed Butter, Arginine HCI, Behenyl Alcohol, Hydrogenated Jojoba Oil, Isopropyl Myristate, Methylglucamine HCI, Cyclohexasiloxane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Ceteareth-20, Glyceryl Stearate, Polysorbate 80, Tocopheryl Acetate, Polyacrylamide, Alcohol, Aloe Barbadensis Leaf Extract, Dimethicone, Oenothera Biennis Oil, Olive Oil, PEG-7 Esters, Squalane, C13-14 Isoparaffin, Tocopherol, Argilla (Magnesium Aluminum Silicate), Laureth 7, Acetylated Lanolin Alcohol, Cetyl Acetate, Xanthan Gum, Disodium EDTA, Tetrasodium EDTA, Camellia Sinensis Leaf Extract, Diazolidinyl Urea, Phenoxyethanol, Methylparaben, Butylparaben, Ethylparaben, Propylparaben, Iodopropynyl Butylcarbamate.


NOTE: These products may NOT be returned. Please make your selections carefully.


Review Summary
1 Reviews
100% (1)
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100% Recommend this product (1 of 1 responses)
By Renee
Livonia, Mi
Smooth Baby Smooth !
January 18, 2023
been using this for 3 or more years, areas I use on face are smooth as they were 5+ years age I am 66 now can't be without it