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CosMedix Refine Plus

We recommend DCL AHA Resurfacing Lotion 20 as a replacement.

CosMedix Refine Plus

We recommend DCL AHA Resurfacing Lotion 20 as a replacement.
Item Code:CMX-2024
Packaging:.5 fl oz (15 ml)
Retail Price:$74.00
Out of Stock


Take your results to the next level for enhanced results with 8% of our Microencapsulated Retinol Complex, fortifying amino acids, and deep replenishing hydrators. Reduce the appearance of fine lines and sun damage, while retaining skin's key moisture. Enhance your results with twice the potency of Refine. Amplified collagen-stimulating and reparative properties make this a potent anti-aging tool.

Skin Type/Concern:
  • Oily
  • Acne
  • Breakout Prone
  • Hyperpigmented
  • Photodamaged
  • Age Management

  • Increases cellular turnover
  • Less irritation/redness than with other retinoids
  • Stimulates collagen/elastin/GAG production
  • Reduces fine lines/signs of aging
  • Improves skin texture and color
  • Anti-acne/antibacterial/anti-sebum
  • Discourages melanocyte grouping

Key Ingredients:
  • Retinol - Encourages skin renewal to reduce the appearance of wrinkles and imperfections

  • Sodium Hyaluronate and Sodium PCA - Help prevent moisture loss

Note: If you have built up your tolerance on this product, the next level up from this in terms of retinol % is Cosmedix Serum 16. It has a 16% Retinol and Retinaldehyde blend and the next level up from Refine Plus.


  • A combination of science and botanical ingredients help firm skin and smooth lines and wrinkles.
  • Conditioning moisturizers help attract and retain vital moisture in the skin.
  • Helps to even skin tone by reducing the look of acne scars, dark spots and hyper-pigmentation.
  • Free radical-fighting antioxidants defend skin from environmental stress that can cause inflammation and damage to collagen and elastin.
  • Acne is caused when oil, hair and dead skin cells clog pores. Ingredients such as Salicylic Acid and AGP Complex help stimulate cell turnover to curb breakouts.
  • Improved texture and proper product absorption is due to exfoliation. When the surface layer of the skin is removed, fresh skin is revealed and can absorb active ingredients easier.
  • AGP Complex a microencapsulated retinol for oily, congested and acne-prone skin encourages skin renewal to reduce the appearance of wrinkles and imperfections.
  • For those with severe gluten sensitivities or Dermatitis Herpetiformis, rest assured this product is gluten free.


After prepping skin with Refine for 60-90 days, you are ready to advance to Refine Plus. Apply a small amount to freshly cleansed and toned skin as tolerated every 1-3 nights, working up to nightly use. Follow with recommended moisturizer.

We do not recommend this product for use in the AM as it may cause skin sensitivity to sun exposure.


Aqua, Hamamelis Virginiana (Witch Hazel) Water, Retinyl Acetate, Alcohol, Glycerin, Sodium Lactate, Helianthus Annuus (Sunflower) Seed Oil, Polysorbate 20, Retinol, Galactoarabinan, Squalane, Sodium Hyaluronate (L), Proline (L), Hydroxyproline (L), Cassia Angustifolia Seed Polysaccharide, Tocopheryl Acetate, Glucuronolactone (D), Sorbitol, Aniba Rosaeodora Wood Oil, Lavandula Angustifolia (Lavender) Oil, Dimethicone, Sodium Pca, Carbomer, Sodium Hydroxymethylglycinate, Citric Acid, Bht, Phenoxyethanol, Potassium Sorbate, Linalool, Geraniol, Limonene, Benzyl Benzoate.